Get the Facts
The Cass Review
Study of Adolescent Gender Dysphoria Treatment (UK)
Independent Review of Gender Identity Services for Children and Young People to provide recommendations on issues related to the delivery of these services.
- Early studies (2015–2016) found no benefits from puberty blockers, with 2020 results confirming no positive outcomes.
- Despite this, puberty blockers became routine in 2014, used on a wider patient group not meeting original research criteria.
- Using a treatment with unclear benefits without further review significantly deviates from standard medical practice.
- Cass is backed by University of York reviews of all the studies and by England’s treatment-advice body (NICE) 2020 reviews of puberty blockers (GnRH analogues) and hormones of the opposite sex. Those papers are not listed as separate Facts cards.